Symbol
Name
ID

Tcra
T cell receptor alpha chain
MGI:98553

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Mouse Phenotypes

decreased T cell proliferation

abnormal thymus cell ratio

abnormal thymus cortex morphology

enlarged thymus cortex

absent thymus medulla

thymus hypoplasia

decreased thymocyte number

enlarged spleen

spleen hyperplasia

abnormal positive T cell selection

abnormal double-negative T cell morphology

increased double-negative T cell number

decreased double-positive T cell number

arrested T cell differentiation

increased B cell number

decreased NK cell number

abnormal T cell subpopulation ratio

decreased CD4-positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

increased CD8-positive, alpha-beta T cell number

decreased NK T cell number

increased NK T cell number

increased gamma-delta T cell number

increased mature gamma-delta T cell number

increased gamma-delta intraepithelial T cell number

absent T cells

increased T cell number

increased activated T cell number

abnormal T cell morphology

abnormal CD4-positive, alpha beta T cell morphology

abnormal CD8-positive, alpha beta T cell morphology

abnormal NK T cell morphology

abnormal memory T cell morphology

abnormal splenic cell ratio

decreased splenocyte number

increased IgE level

increased IgG1 level

decreased IgG2a level

decreased IgG level

increased immunoglobulin level

abnormal T cell physiology

abnormal NK T cell physiology

Availability

Mouse Genotype

Tcra^tm1Mass/Tcra^tm1Mass

Tcra^tm1Mjo/Tcra^tm1Mjo

Tcra^tm1Mom/Tcra^tm1Mom

Tcra^tm1Mom/Tcra^tm1Mom
Tg(TcraAV19AJ33)1Shima/?

Tcra^Ln1Ogu/Tcra⁺

Tcra^Ln3Jae/Tcra⁺

Tcra^tm1Mjo/Tcra⁺

Tg(TcraAI4)1Dvs/0

Tg(TcraDN32D3)#Alhn/0

Tg(Tcra2B4)1Mmd/?

Tg(TcraAV19AJ33)1Shima/?

Tcra^tm1Cgn/Tcra^tm1Cgn
Tg(Mx1-cre)1Cgn/0 (conditional)

Tcra^tm1Cgn/Tcra^tm1Mass
Tg(Mx1-cre)1Cgn/0 (conditional)

Tcra^tm1Mass/Tcra⁺
Tg(Cd4-cre)1Cwi/0 (conditional)

Tcra^tm1Mass/Tcra⁺
Tg(Nes-cre)Wme/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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